Schizophrenia may not be a single disease, but the result of a diverse set of related conditions. Modern neuroscience is beginning to reveal some of the genetic and environmental underpinnings of schizophrenia; however, an approach less well travelled is to examine the medical disorders that produce symptoms resembling schizophrenia. This book is the first major attempt to bring together the diseases that produce what has been termed 'secondary schizophrenia'. International experts from diverse backgrounds ask the questions: does this medical disorder, or drug, or condition cause psychosis? If yes, does it resemble schizophrenia? What mechanisms form the basis of this relationship? What implications does this understanding have for aetiology and treatment? The answers are a feast for clinicians and researchers of psychosis and schizophrenia. They mark the next step in trying to meet the most important challenge to modern neuroscience – understanding and conquering this most mysterious of human diseases.
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abnormalities abuse Acta activity acute adrenoleukodystrophy adult Alzheimer’s disease amphetamine antipsychotic Arch Gen Psychiatry Arch Neurol associated auditory hallucinations basal ganglia behavioral Biol Psychiatry brain calcification cannabis cerebral Charles Bonnet Syndrome chosis chotic chromosome chronic Clin clinical clozapine cocaine cognitive colleagues correlates cortex cortical deficits delirium delusions dementia diagnosis DISC1 dopamine doses drug dysfunction effects epilepsy etal evidence frontal functional gene Genet hallucinations haloperidol Huntington’s disease illness impairment increased ketamine lesions linkage MDMA mental metabolic metachromatic leukodystrophy mitochondrial mutation neuroimaging Neurol Neurosurg Psychiatry neurological neuropsychiatric Neurosci Niemann-Pick disease NMDA olanzapine onset pathology patients with schizophrenia phencyclidine prefrontal prevalence psychiatric disorders psychiatric symptoms Psychiatry psychotic disorders psychotic symptoms quetiapine receptor regions reported risk factors risperidone Schizophr Res schizophrenia schizophrenia-like psychosis seizures substance symp syndrome temporal lobe tion treatment tumors VCFS visual hallucinations Wilson’s disease