presence of the streptococcus. The system, already weakened by the typhoid invasion, becomes impotent to destroy, by phagocytosis, the harmful steptococcus, and to prevent the development in the system of what are really primary local cultures of the germ. Therefrom comes the danger of a general invasion with the recrudescence of all the constitutional symp toms. In the second set of cases, the association of germs appears to exist from the start of the disease, and there results a sort of strepto-typhoid, the prognosis in which is very grave, and the effects of which very largely expend themselves upon the nervous system. This form of infection can determine the existence of typhoid fever without its classical intestinal lesions. The bacteriological examination reveals the presence of the typhoid bacillus in all the viscera and in the nervous system. At the same time the streptococci are found in large numbers in the spleen and brain. THE POISON THEORY AND PHAGOCYTOSIS. Sanarelli says (Centralb. f. Bakt. u. Paras.) he showed in Number XIV-XVI of the same journal how the lymph from the posterior lymph sac of the frog possessed the property of rendering anthrax foci inert whether these latter contained spores are not. Pieces of the spleen taken from animals dead of anthrax and introduced beneath the frog's skin, or cultivations brought into contact with this lymph (free from leucocytes), lose their virulence. The lymph acts, not upon the vitality, but upon the virulence of these organisms. Experiments have not shown that the lymph is a true specific capable of destroying the anthrax foci, but that it is an unfavorable cultivation medium. The organisms rapidly regain their virulence when transferred to a suitable medium. All are agreed that the cells quickly seize upon the bacteria, for they may be seen containing bacteria three to four hours after inocula tion. Even while in the cells, the organisms may excrete toxic substances, which irritate the heat centers and cause a rise of temperature. Metschnikoff has certainly seen movements in the bacilli in these cells, and this must be evidence of life. He has also seen the partly taken up bacilli grow and capable of forming virulent cul tures. The question arises as to the value of phogocytosis as compared with the bacteria-killing properties of organic fluids in refractory animals. Sanarelli says that he cannot believe, with the exclusive supporters of this poison theory, that the leucocytes can only take up the bacilli when these are dead, nor yet with the extreme partisans of phagocytosis that there is a veritable conflict between the leucocytes and the bacteria. He prefers to think that, owing to the unfavorable soil, the pathogenic organisms have their growth checked, and that the leucocytes gradually take them up and remove them from the body. This confirms Petruschky's view that the bacteria-killing action is able to explain of itself, and without the least help from the leucocytes, the immunity of frogs against anthrax.-British Med. Four. 2. 2 2 I 3 5. 6. 1 7. I 8. 9. I 10. II.. 12.. 13. 14. 15. I 16. 2 22 24 ONE WAY TO ADVERTISE. There is a widespread popular belief that physicians do not advertise. This is not strictly speaking, in accord with the facts of the case. Without advertising one's profession, qualifications, and ability, success is either not attained at all, or comes so slowly and so late that it can scarcely be counted a success. Bringing and keeping one's self before the public is as necessary in a physician's work as in that of any other man-but it is not necessary for him to secure the necessary publicity in the usual ways of trade. The conscientious, painstaking, and wide-awake man who does not forget what is due to himself, neglects no opportunity to do the best he can in every case which comes to him, and thus make his work, his selfdenial, his gentlemanliness, all serve as an advertisement of his worth and bring him work. He who writes, speaks, lectures, operates before bodies of physicians or students is constantly advertising himself whether he will or not. He is making an impression which will in Mortality Report for the week end- fluence his professional career in one Now, one would not suppose that this form of advertising would pay. A man is not at all likely to refer patients to a specialist who is known to him simply through being bored twelve times a year by the receipt of some cheaply printed cards when he is probably looking for a check in the mail that brings them. That it does pay, however, would seem to be indicated by the fact that imitators have sprung up. Men equally unknown to fame, but who evidently have their printing done in the same office in equally large quantities, and mailed in numbers consistent with the limits of one cent postage. The only explanation of the success of the scheme which presents itself to us is hat a sufficient number of cards sift out on the way through the mails and are picked up by the thoughtless, or that enough reach servants and ashmen by way of the waste-basket to return a profit on the outlay. We do not object to a physician stating his specialty on his card, if he has a specialty and desires to state it, but when he regu- A SUIT FOR DAMAGES. A suit against the New York Hos pital for damages sustained by a boy patient who was alleged to have suf fered amputation of the thigh as a resul of mortification of the leg from tigh bandaging for fracture, has been non suited upon the ruling that no action fo malpractice can hold against a charitabl institution which uses every care i the selection of competent surgeon to treat its patients. -N. Y. Med. Record SUBSCRIPTIONS to LANCET-CLINI may commence at any date. La Grippe DURING LAST YEARS EPIDEMIC ANTIKAMNIA SECURED THE DESIRED RESULTS FOR HISTORY LITERATURE ADDRESS. THE ANTIKAMNIA CHEMICAL CO., ST. LOUIS, MO., U. S. A. Tancet-Clinic A Weekly Journal of Medicine and Surgery. NEW SERIES Terms, 83.50 per Annum. Entered at the Post Office at Cincinnati, Ohio, as second-class matter. Vol. XXVIII. No. 11.} Cincinnati, March 12, 1892. WHOLE VOLUME LXVII. 348 A QUESTION OF ETHICS AND EQUITY. TRANSLATIONS. MOLIERE AND GUI PATIN.-Chapter II. By Thomas C. 334 336 A Salve to Quiet the Itching of Measles, Scarlatina nus. Contents continued on Advg. p. 4. See Advertisement " VIN MARIANI" on Insert page x. 2 Million Bottles filled in 1873. 343 345 ESSENCE OF PEPSINE ingredient of the GASTRIC JUICE, Extracted (FAIRCHILD). Directly from the Peptic Glands of the Stomach. Apollinaris "THE QUEEN OF TABLE WATERS." "Much favored by her Majesty." -WORLD, LONDON. "The best beverage." -TRUTH, LONDON. BRITISH MEDICAL JOURNAL. "Cosmopolitan.” "Cheap as well as good." "The demand for it is great and increasing." 3 -THE TIMES, LONDON. "What a boon it would be to the Med ALE AND BEEF ical Profession if some reliable Chemist would bring out an Extract of Malt in combination with a well-digested or peptonized Beef, giving us the elements of Beef and the stimulating and nutritious BLOOD MUSCLE portions of Ale." SOLD BY DRUGGISTS. DR. J. N. LOVE, St. Louis, says:-Since the product has been brought under my notice I have prescribed it in the sick room to one hundred recorded cases. Patients who have suffered from loss of flesh, dependent upon various forms of Dyspepsia, when they partook of the Ale and Beef, "Peptonized," felt much benefited. I have now under my observation three patients, the victims of the dread disease pulmonary consumption, in which the digestive tract is demoralized, and in which it seems impossible to bring to bear any form of nutrition which is not disgusting to the patient. In all these cases the drink is a Godsend. A number suffering from prostration, following serious attacks of the recent epidemic of La Grippe accompanied by loss of appetite and a general feeling of worthlessness, were braced up and greatly benefited immediately after commencing the use of the Ale and Beef, "Peptonized." In half a dozen cases of typhoid fever, in which everything else was distasteful to the patient, the Ale and Beef, "Peptonized," pleased the palate, and nourished and strengthened the patient admirably. I feel personally under obligations to those who have presented so valuable a product to the medical profession, and many a tired and faded patient will be revived and strengthened by the life-giving drink, Ale and Beef, "Peptenized," which is a happy union, in that it contains mildly stimulating (alcohol in small quantity), gently tonic (a modicum of the active principle of hops), decidedly nutrient (malt and beef) and positive digestive (diastase and peptonoids) propertiesa union which is in harmony with well-known physiological principles, and will in my judgment be indorsed by careful bedside clinicians. Dr. W. F. HUTCHINSON, Providence, R. I., says:-I have used Ale and Beef, "Peptonized," very freely during the past few months and am delighted with the effect obtained. One case was that of a hopeless paralytic, unable to retain any food and steadily failing, for whom I ordered one bottle daily. Her stomach never rejected it and has steadily gained since she commenced using it. PROF G. A. LEIBIG says: -J. MILNER FOTHERGILL, M.D. DEAR SIRS:-Answering yours of the 8th inst., will say that I have used the Ale and Beef, "Peptonized," in both hospital and private practice, and am much pleased with it. My house surgeons (Drs. F. R. Smiley and Geo. F. Hamel) inform me that it agrees with the stomach in cases where food can not be retained, and this agrees with my own experience. I had one case of a delicate lady with a forming pelvie abscess which involved the ovary. There was constant vomiting and retching. She retained the Ale and Beef, "Peptonized." This, after I had tried a number of things which had failed. She drank it steadily for a month, and it seemed to be, in her case, food, medicine and stimulant, all in one. It is an excellent thing. Keep up the good quality of the preparation and it will readily sell. Very respectfully, WILLIS P. KING, M.Ď., Ass't Chief Surgeon, Mo. P. Ry. "A careful chemical examination of the Peptonized Ale and Beef shows a much larger per cent. of nitrogenous blood and muscle-making matter over all other malt extracts, and that it is also rich in Diastase, giving it the power to digest BLOODA Starch Foods." PREPARED BY THE ALE BEEF COMPANY, DAYTON, O., U.S.A. Two full-sized bottles will be sent FREE to any physician who will pay express charges. In Corresponding with Advertisers, please mention THE LANCET-CLINIC. |