ity of the urine to be examined is taken at age of active phosphorio acid, that is, the 15 deg. C. If the temperature differs from amount which is capable of neutralizing an this figure, a correction is made according to equal atomio weight of base, in E, whiob is a printed table. The total acidity, that is to the excess of urinary density over that of say, the acidity from all sources, is now cal. water. When the readings show that both calated, and is expressed in terms of the RA and R P are below the normal, the ex. amount present in a hundred parts of the planation is simple enough. It is that there excess of the urine over that of distilled water is an insufficient quantity of phosphorio aoid at the same temperature. In this way the in the blood and the symptoms are there. errors inseparable from the varying amount fore due, at least in part, to the deposition of water in different samples of the same of earthy phosphates in certain organs and person's urine are altogether avoided. The tissues, the treatment resolving itself into degree of dilution of a specimen, always the administration of phosphoric acid in hitherto a matter of difficulty may thus be gradually increasing amounts. An examin. disregarded. Thus, if the specimen in ques. ation according to Joulie's method will not tion shows a speoific gravity of 1.020, the ex. only establish the fact of byperacidity or subcoss (which is called E) is 20, because the acidity, as the case may be, but will give us density of the water at 15 deg. C. is kpowp the degree of the deviation from the normal to be 1.000. The total acidity is calculated and at the same time inform us of the proper by means of precipitation with a standard line of treatment. solution of sucrate of calcium (10 grammes

Determination of Lead in the Urine.-A. of powdered obalk and 20 of sugar to a liter of

Lederer, Chicago (Jour. A. M. A., May 26), distilled water). The figure thus obtained is

remarks on the disadvantages of tbe methods Α

usually employed in testing for lead in the called A. Thus we have — x 100 = R A

urine, and describes the test which he uses E

and for which he claims special advantages (i.e., the percentage of total acidity in E).

in accuracy, quickness and simplicity. It The normal standard for R A as worked out

consists in precipitating the lead, free from by Joulie is between 4 and 5-as nearly as

all organic matter, by means of potassium possible 4.5. But, as we have already seen,

seen, sulphate in sulphurio acid solution, washing

unhee in aninho this total acidity is from our point of view A

down the insoluble sulphate thus precipitamatter of secondary importance. What we

ted with distilled water, and passing hydrowish to ascertain is the amount which the

gen sulphid gas through it. The slightest acid phosphates contribute to this acidity;

yellowish-brown discoloration proves that in other words, how much of this is service

lead is present. A great advantage of this able phosphoric acidity, and how much,

test, he says, is that even if bismuth is presof it is organic, fortuitous, and undesira.

ent, it will not affect it, nor will any other ble. The next step is therefore to determine

substance that is likely to be present. By the amount of phosphoric acid, combined

comparison with artificial lead solutions con. and uncombined, which is present in the

tuining 1 mg., 2 mg., 3 mg., etc., of lead, given speoimen. This is calculated by the

per liter, a simple quantitative colorimetric olassical moethod with nitrate of uranium and

method oan be established. ferrocyanide of potassium, and is expressed in terms of the amount present in 100 parts Mortality After Prostatectomy.-B. Tenney of the excess of the urinary density over that and H. M. Chase, Boston (Jour. A. M, A., of water at the same temperature. If we call May 12), bave analyzed the mortality statis. the total phospbatio contents thus obtained tios of over a thousand cases of prostatec


tomy, with special reference to the mortality, P, we have the following formula – x 100 counting as fatal cases all within six weeks


of the operation and excluding such statis= R P (i.e., the ratio of the phosphates; in tios as cover only a shorter period of observaother words, the percentage of total phos- tion, though they might give a more favora. pbatic contents in E). The normal standard ble result. The mortality by the perineal for R P as estimated by Joulie is between 11 operation in their statistics is slightly less and 11.5, as noarly as possible 11.17. In than that of the suprapubic method, and the order tc find what we are in search of, name- difference is very much less in the statistics ly, the amount which the phosphates con of their collection than in those collected by tributed to the total acidity, it is necessary to Proust, Watson and Escat. There is also a

RP 11.17 decidedly rising mortality from the sixth to divide R P by RA, thus: --=--= the eightb decade, the percentages being, re

RA 4.5 spectively, 5.8, 9.5 and 15, thus indicating 2.45. This represents the normal percent. the advantages of early operation. The sta

tistics also show certain fatal periods; in the PROF. WILLIAM H. WELCH, of Baltimore, 73 deaths more occurred in the first forty has been elected a member of the Board of eight hours than in any other two days, 23 Trustees of the Carnegie Institution, in place in all. In the seventh, eighth and ninth of the late Secretary of State Hay. days there were 12 deaths; on the tbirteenth, fourteenth and fifteenth there were 6 deaths, A NEW SOURCE OF ALCOHOL.-A Madaand from the twentieth to the twenty-second gascar plant, jutropha manihot, is the source days, inclusive, 7 deaths. Two-thirds of all of starch extensively used in the manufacthe deaths occurred during these fatal periods. ture of glues. It also furnishes food for both The duration of life following the two opera man and beast, and promises to rank bigb tions is almost identical. The favorable sta- as a source of alcohol. tistios of certain operators are noted. Out of the 617 perineal operations, we find two men

REGENERATION OF Lost Parts.—T. H. doing 211 operations and losing 2 cases within Morgan, New York (Jour. A. M. A., May 5), 12 days, as compared with 206 of the other reviews the facts and theories regarding the operators with 22 deaths in the same period. regeneration of lost parts in certain animals Including the suprapubic operations, there is and the failure to do so in others. The ques. a total of 45 fatalities in 790 operations within tion, he says, is possibly of some practical the same period. These two men mentioned importance, for if we could determine why do not appear to have used the most rapid man, dues not replace a lost arm or leg, we method or to bave specially selected their might perhaps go further and discover bow cases. The presence of vesical calculus did artificially to bring about this process. Renot seem to have any favorable influence on generation appears to bim as only a pbase the mortality, as claimed by Moullin, Riobard. of the general phenomenon of growth, and son and others. The authors think that many if this is the case, why, he asks, does an ani. of the fatalities must have been avoidable, mal that has ceased to grow begin to reand insist on the importance of due prep generate rapidly when a part has been rearation of the patient, special care in the moved If we turn the question around the selection and use of the anesthetic, and other way and ask, why does an anima! greater attention to the after-care. A pros. stop growing at a certain stage, we may attatectomy is not a completed piece of handi. tack the problem at closer quarters. It is work, like most clean laparotomies and dis evidently not because the cells bave lost the secting operations, but needs constant atten. power of growth: their power in this direction for forty-eight hours especially, and later tion seems unlimited, nor oan it, as he shows, at intervals.

be entirely attributed to an equilibrium between food supply and consumption. The

question seems to be one of inbibition, and Dr. H. McC. Johnson has been appointed

he suggests, as a possible explanation of to the St. Loius Board of Health to succeed

the cessation of growth, a definite response Dr. H. W. Bond, who is now Health Com.

to a condition of mutual pressure or tension missioner.

of the cells on each other. When this is AN AMBULANCE ADVENTURE.-Some two

reached growth stops, and when we alter the years ago Mr. E. E. Carruthers, of Scranton,

tension by removing a part it begins again. Pa., having been injured in East St. Louis,

The facts of regeneration of lost parts in the was removed in an ambulance. He alleged

vertebrates are given and the reason why it at the time that he had been robbed of a

fails in mammals and in man are discussed. pocketbook oontaining $150. On May 10th

Morgan does not think tbis can be due to the ambulance was undergoing repairs when

greater complication of structure or to any on tearing way the lining, a pocketbook con.

process of natural selection. He thinks it taining $150 and Mr. Carruthers's card was

more probably due to tbe fact that different found therein. The amount was forwarded

tissues have very different rates of regenerato bim by check.

tion. In the higher mammals the failure to

regenerate is observed in cases in which carTHE STATE PENITENTIARY HOSPITAL. tilage begins to change to bone, and be At a meeting of the State Board of Prison thinks the main trouble is in the slowness of Inspectors, at Jefferson City, on May 9th, it the bones to regenerate in time with the other was decided to push ahead with the enlarge tissues. He says: "If the tissue in man still ment and modernization of the old prison possess the power to regenerate, may we not hospital, for which purpose $50,000 was ap hope in time so to adjust their rate of regen. propriated by the last legislature. The ward. eration that the replacement of a lost limb en expects to bave the building completed may be produced? I can not but think that by the end of the year.

some day this may be accomplished."'


(C2H204 + C3H803) ABSOLUTELY HARMLEss. Indorsed and Successfully used by leading Physicians in the


CONTAGIOUS DISEASES of the STOMACH and INTESTINES. In order to prove the efficiency of GLYCOZONE, I will

Prepared only by send a $1.00 bottle free to Physicians accompanying their request with 25c. to pay forwarding charges. · A copy of the 18th edition of my book of 340 pages, on the sence of Pathogenic Germs,” containing reprints of 210 unsolicited clinical reports, by leading contributors to Medical Chemist and Graduate of the " Ecole Centrale des Literature, will be mailed free of charge to Physicians

Arts et Manufactures de Paris ” (France) mentioning this Journal.

57-59 Princo Street, NEW YORK.

tharles Marchando

la eee

" Rational Treatment of Diseases Characterized by the Pre

Look well to your prescriptions-a careless or dishonest pharmacist may ruin your reputation.

A Valuable Cathartic and Intestinal Tonic

Pil. Cascara Cathartic

(Wm. R. Warner & Co.)

Formulated by Dr. Hinkle. Introduced by FORMULA

us. Presented by the most eminent practition-
Aloin . . . aa 4 gr.

ers with unexceptional success.
Podophyllin . . 1-6 gr.
Ext. Belladon. 1.8 gr.
Strychnin, . . 1-60 gr.

Specify Warner & Co. and avoid
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cheap imitations.





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THE MEDICAL FORTNIGHTLY License. – Many local druggists have deter

ST. LOUIS PHARMACISTS AND THE LIQUOR LICENSE.—Many local druggists have deter

mined to give up the sale of alcohol and those . A Commopolitan Blweekly for the General Practitioner

medicines classed as intoxicating beverages The Medical Fortnightly is devoted to the progress of the

by the internal revenus collector, with a view Practice and Science of Medicine and Surgery. Its aim is to prerent topics of interest and importance to physicians, and to this of fighting the $624.00 a year license de. and, in addition to & well-selected corps of Department Editors, it has secured correspondents in the leading medical centers of manded by the excise commissioner from Europe and America. Contributions of a scientifio nature, and

those who sell intoxicating liquors. It is in. ' original in character, solicited. News of Societies, and of interesting medical topics, cordially invited.

teresting to note that the St. Louis West End Advertising forms close on the first and fifteenth of each month. Time should be allowed to submit proof for correction

Grocers' Club has an opinion from Lieuten. Advertising rates on application.

ant-Governor Charles P. Johnson to the efRemittances and business communications should be addressed to the Fortnightly Press Co.

feot that this saloon license should not be deSubscription, $2.00 a year, in advance, including postage to any part of the United States, Mexico and Canada. Postage to manded from grocers. His opinion in full foreign countries in the Universal Postal Union, including, New is given in the Eli Grocer and General Mer. foundland. $1.00 a year additional. Entered at the St. post-office as second-class matter.

chant, of St. Louis, for April 14, page 5. The Medical Fortnightly will not be discontinued at expira tion of subscription, as many of our readers prefer not to have their files broken on account of failure to remit. Unless we receive a distinct request to discontinue, and payment for all ar NATURE'S BEST TONIC.-Laughter is un. reara.ges, this magazine will not be discontinued.

Subscriptions may begin at any time; volumes end with doubtedly one of Nature's greatest tonios. June and December. Contributors should understand that corrected typewritten

It brings the disordered faculties and funccopy is essential to clean proof and prompt publication, and is tions into barmony, it lubricates the mental much more 'satisfactory than manuscript. Original articles should be as condensed as justice to the subject will allow. bearings, and prevents the friction wbioh

. Editorial offices in St. Louis, Jacksonville, and St. Joseph, monotonous, exacting business engenders. where specimen copies may be obtained, and subscriptions will be received.

It is a divine gift bestowed upon us as a life Contributions and books for review should be addressed to the editori, 319 and 320 Century Building, St. Louis, Mo. preserver, a health promoter, a joy generator,

a success maker. Life with the average man MEDICAL MISCELLANY is too serious at best. · Never lose an oppor

tunity for relaxation from the stress and The establishment of a state tuberculosis

strain of your business or profession. Every sanatorium in Iowa has been facilitated by draught of laughter, like an air-cushion, the passage of a bill in the legislature appro. eases you over the jolts and the hard place priating $50,000 for the purpose.

on life's bighway. Laughter is always A BULLETIN issued by the Interstate Com.

healthy. It tends to bring every abnormal merce Commission shows that during the

condition baok to the normal. It is a panamonths of July, August and September last

cea for heartaches, for life's bruises. It is a 1053 were killed and 16,386 injured among

life prolonger. passengers and employees of steam roads in The United States...


THAT IS PRODUCING RESULTS. —G. Shear. Paris, in his latest list of radium prepara

man Peterkin (Seattle, Wash.) says the edutions, quotes the following prices: Pure ra.

cation of the individual in the law of sex is dium bromide, one milligramme, $80; one

the only feasible means, at our present stage centigramme, $800; one decigramme, $8,000;

of evolution, of lessening or preventing ven. one gramme, $80,000. To this must be

ereal diseases. From sociologic, economic, added the import duty of twenty-five per

ethic and physiologic laws, eto., scientifio cent. At this rate the commercial value of

facts are taken as premises, and from these one grain of radium in the United States

conclusions drawn to prove that this fact would be more than $5,000.

must be recognized. With these principles

as a working basis, pamphlets-five in numIn response to a suggestion from the Na. ber-have been issued by a Committee on tional Association for the Study and Preven. Prophylaxis of Venereal Diseases of the tion of Tuberculosis, President Roosevelt bas Washington State Medical Association. The appointed a committee to investigate the san. pampblets are appended in full, and Dr. itary condition existing in the government Peterkin gives the reason for using them as offices and workshops, with a view to recom. a means of disseminating such knowledge mending measures for the prevention of tu- and for presenting the amount and characberculosis. The members of the committee ter of knowledge they contain. The posi. are: Surgeon-General Robert M. O'Reilly, of tion is taken that business principles of the U. Š. Army; Surgeon-General P. M. today can be ethically applied in leading Risey, of the U.S. Navy; and Surgeon-Gen. man, who must and will niake his own moreral Walter Wyman, of the Public Health ality, to the next succeeding evolutionary and Marine Hospital Service.

stage of his morality.-American Medicine.

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