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A NEW CINCHONA ALKALOID, FROM

CUPREA BARK.

The London Pharmaceutical Journal and Transactions of Dec. 17th, p. 497, has two articles upon a new alkaloid found in the recent coppery colored Cinchona Bark which has come in large quantities from South America, and is much used by makers of Salts of Quinia. One paper is by Messrs. B. H. Paul and A. J. Cownley, and the other is by Mr. W. George Whiffen.

These papers concur in their description of an alkaloid not before known, but which is very much like quinia. The sulphate is very much like the Sulphate of Quinia, but some of the other salts resemble those of Cinchonidia. Its chief characteristic as stated by Mr. Whiffen is its action on polarized light. It rotates the polarized ray to the left more powerfully than Quinia, or than any of the alkaloids of Cinchona, and therefore he proposes to distinguish it as " ultra-quinine.” It has not been separated in any considerable quantity as yet, and nothing seems to be known of its therapeutic value. From its apparent position in the scale of the Cinchona alkaloids, it should not be inferior to quinia.

AN

EPHEMERIS

OF

MATERIA MEDICA, PHARMACY,

THERAPEUTICS

AND

COLLATERAL INFORMATION.

MARCH, 1882.

BY

EDWARD R. SQUIBB, M. D.
EDWARD H. SQUIBB, S. B., M. D.
CHARLES F. SQUIBB, A. B.

BROOKLYN, N. Y.

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