Sidebilder
PDF
ePub

SOME NEW SULFONPHTHALEIN INDICATORS.

A Preliminary Note.

By BARNETT COHEN, Associate Chemist, Hygienic Laboratory, United States Public Health Servico.

For the determination of H-ion concentration by the colorimetric method, the indicator series of Clark and Lubs has been found extremely useful. Improvement of this indicator series may be sought in two ways: One is the introduction of suitable indicators to fill gaps in the pH scale not now adequately covered; the second is in the substitution of a sulfonphthalein compound for methyl red. As is well known, methyl red is much less stable than the sulfonphthalein indicators and is readily reduced. Clark and Lubs retained it in their series because methyl red was at that time indispensable in covering an important pH range.

The following new sulfonphthalein indicators are suggested as filling the above requirements. The dyes were synthesized in the usual way, complete details of which will be published later.

[blocks in formation]

Brom cresol green covers almost perfectly the range of methyl red, the apparent dissociation constants in terms of pH being 5.00 and 4.95, respectively.

Brom phenol red and chlor phenol red, because of their color changes (yellow to red), may be used advantageously where the dichromatism of brom cresol purple is a disturbing factor.

The protein and salt errors of these new indicators remain to be determined. It is tentatively assumed that such errors are of the same magnitude as those of the other sulfonphthaleins now in use.

INFLUENZA IN THE UNITED STATES.

The following table shows the numbers of cases of influenza reported by State health officers, by telegraph, for the week ended January 27, 1923, compared with similar reports for the corresponding week of 1922, 1921, and 1920.

Similar tables covering the period from October 1, 1922, to January 20, 1923, were published in the Public Health Reports

December 29, 1922, page 3204; January 12, 1923, page 61; and
January 26, 1923, page 141.

Cases of influenza reported by telegraph by State health officers for the week ended Jan. 97,

1923, coni parud with similar reporis for the corresponding week of the years 1922, 1921, and 19:20.

[blocks in formation]
[merged small][merged small][merged small][merged small][merged small][merged small][merged small][merged small][merged small][merged small][merged small][merged small][merged small][merged small][ocr errors][merged small][merged small][merged small][merged small][merged small][merged small][merged small][merged small][merged small][merged small][merged small]

New England Division:

Maine...
Massachusetts.
Vermont.

Connecticut.
Middle Atlantic Division:

New York (exclusive of New York City).
New York City.

New Jersey.
East North Central Division:

Indiana.
Illinois

Wisconsin
West North Central Division:

South Dakota.
Nebraska....

Kansas.
South Atlantic Division:

Delaware.
Maryland.
District of Columbia.
West Virginia...
Georgia.
Florida.

South Carolina.
East South Central Division:

Kentucky..
Alabama..

Mississippi.
West South Central Division:

Arkansas.
Louisiana

Texas.
Mountain Division:

Colorado (exclusive of Denver).

New Mexico..
Pacific Division:

Washington.
Oregon..
California.

38 1,602

100 192

4 107

4

[ocr errors]

729

617

100

[blocks in formation]

(1)

1, 547 (1)

[merged small][merged small][merged small][merged small][merged small][ocr errors][merged small][merged small][merged small][merged small][merged small][merged small][merged small][ocr errors][merged small][merged small][merged small][merged small][merged small][merged small][merged small][merged small][ocr errors][merged small][merged small][merged small][merged small]

i No report.
2 11 cases reported for two weeks ended Jan. 28.
8 69 cases reported for two weeks ended Jan. 28.

The following table shows the numbers of deaths from pneumonia (all forms) and influenza, combined, in certain large cities of the United States for the weeks ended January 13 and 20, 1923, as reported by city health officers.

A similar table covering the period from December 3, 1922, to January 6, 1923, was published in the Public Health Reports January 19, 1923, page 101.

Deaths from pneumonia (all forms) and influenza, combined, in large cities of the l'nited

States, January 7 to January !0, 1923, inclusive.

[graphic]

2 6 13

25

6

1 8

21 213

3

[ocr errors]

Alabama:

Birmingham..

Mobile.
California:

Berkeley
Long Beach
Los Angeles.
Oakland..
Sacramento...
San Diego.

San Francisco.
Colorado:

Denver.
Connecticut:

Bridgeport.
Hartford..
New Britain..
New Haven..

Waterbury
District of Columbia:

Washington..
Florida:

Tampa..
Georgia:

Atlanta
Augusta.

Savannah
Illinois:

Chicago.
East St. Louis.
Peoria...
Rockford

Springfield.
Indiana:

Fort Wayne.
Gary
Indianapolis.
South Bend.

Terre Haute.
Kansas:

Topeka..

Wichita
Kentucky:

Covington

Louisville.
Louisiana:

New Orleans.
Maine:

Portland..
Maryland:

Baltimore.
Massachusetts:

Boston..
Cambridge.
Fall River.
Haverhill.
Holyoke.
Lawrence.
Lowell.
Lynn..
New Bedford.
Somerville
Springfield

Worcester.
Michigan:

Detroit
Flint..
Grand Rapids.
Saginaw...

[ocr errors]

176

9 14

6

2

3 2 13

TYPHOID FEVER, MINNESOTA, 1921.--CORRECTION. In the table on page 3206 of Public Health Reports for December 29, 1922, the number of deaths from typhoid fever in Minnesota during 1921 was given as 888. This number should have been 88. The rate given, 3.6 per 100,000 population, was computed on the basis of 88 deaths.

Examination for Entrance into the Regular Corps of the Public Health

Service.

Examinations of candidates for entrance into the Regular Corps of the United States Public Health Service will be held at the following-named places on the dates specified:

Chicago, Ill., March 12, 1923.
San Francisco, Calif., March 12, 1923.

Washington, D. C., March 12, 1923. Candidates must be not less than 23 nor more than 32 years of age, and they must have been graduated in medicine at some reputable medical college, and have had one year's hospital experience or two years' professional practice. They must pass satisfactory physical, academic, and professional examinations before boards of commissioned medical officers.

Successful candidates will be recommended for appointment by the President, with the advice and consent of the Senate.

Requests for information or permission to take this examination should be addressed to the Surgeon General, United States Public Health Service, Washington, D. C.

Week ended

DEATHS DURING WEEK ENDED JANUARY 20, 1923. Summary of information received by telegraph from industrial insurance companics for

week ended January 20, 1923, and corresponding week of 1922. (From the Weekly Health Inder, January 23, 19.3, issued by the Bureau of the Census, Department of Commerce.)

Corresponding

Jan. 20, 1923. week, 1922. Policies in force....

50, 969, 269 48,027, 683 Number of death claims.

10,992 Death claims per 1,000 policies in force, annual rate...

11.2 Deaths from all canses in certain large cities of the United States during the week ended

January 20, 1923, infant mortality, annual death rate, and comparison with cortesponding week of 1922. (From the Weekly Health Indes, January 23, 1923, issued by the Bureau of the Census, Department of Commerce.)

9, 181

10.3

City.

Estimate
population

July 1,
1923.

Week ended

Annual
Deaths under

Infant
Jan. 20, 1923. death

1
year.

morrate per

tality 1,000,

rate, corre Week Corre weck Total Death sponding ended sponding ended deaths. rate. week Jan. 20, week

Jan. 20, 1922. 1923. 1912. 1923.2

1,038

Total.....
28,724, 833 8,217 14.9 14.1

966 Akron, Ohio..

3 203, 433 36 9.0

&3
14

6

166 Albany, N. Y

117.375
19.5 184

3

111 Atlanta, Ga..

222, 963 104 24. 3 16.4

21

12 Baltimore, Md.

773, 580

252
17.0 16.1

35 106 Annual rate per 1,000 population.

Deaths under 1 year per 1,000) births-an annual rate based on draihs under 1 year for the week and estimated births for 1922. Cities left blank are not in the registration area for births.

Enumerated population Jan. 1, 1920.

361

Deaths from all causes in certain large cities of the l'nited States during the week ended

January 20, 1923, infant mortality, annual death rate, ond comparison with corresponding ucek of 1922. (From the Weekly Health Inder, January 23, 1923, issucd by the Bureau of the Census, Department of Commerce.)-Continued.

City.

Estimated population July 1, 1923.

Week rnded

Annual
Deaths under

Infant
Jan. 20, 1923. death

1 year.

morrate per

tality 1.000,

rate, corre Week Corre week Total Death sponding endel sponding ended dcaths. rate.

week
Jan. 20, week

Jan. 20, 1922. 1923. 1922. 1923.

11

61 304

46 132

9 39

[blocks in formation]

16. 17.5 15.3 11.6 14.1 20. 1 12. 2 17.1 12. 1 14.0 14.6

&7 16. 4 11,5

10 100

62.3
166
205
102
32

[blocks in formation]
[ocr errors]

108 46

[blocks in formation]

128 60

[blocks in formation]

79

62

229

92 36 SO 37 115 211 89 40 85 105 8S

5 17

3 10 17 7 1 12 16

67 119 70

99 51

Birmingham, Ala.
Boston, Mass.
Bridgeport, Coon.
Bualo, N. Y.
Cambridge, Mass..
Camden, NJ
Chicago, Ill.
Cincinnati, Ohio.
Cleveland, Ohio.
Columbus, Ohio.
Dallas, Tex
Dayton, Ohio.
Denver, Colo
Detroit, Mich.
Duluth, Minn.
Erie, Pa..
Fail Riser, Mass.
Flint. Mich.
Fort Worth. Tex.
Grand Rapids, Mich.
Houston, Tex.
Indianapolis, Ind..
Jacksonville, Fla.
Jersey City, NJ
Kansas City, Kans.
Kansas City, Mo.
Los Angeles, Calif.
Louisville, Ky.
Lowell, Mass.
Memphis, Tenn.
Milwaukee, Wis.
Minneapolis, Minn
Sashville, Tenn
New Bedford, Mass.
New Haven, Conn.
New Orleans, La..
New York, N. Y

Bronx Borough.
Brooklyn Borough..
Manhattan Borough.
Queens Borough.

Richmond Borough.
Newark, NJ..
Norfolk, V'a.
Oakland, Calif.
Omaha, Nebr.
Paterson, N.J.
Philadelphia, Pa.
Pittsburgh. Pa.
Portland, Oreg.
Providence, R. I.
Richmond, Va.
Rochester, N. Y
St. Louis, Mo..
St. Paul, Minn.
Salt Lake City, Utah.
San Antonio, Tex
San Francisco, Calis.
Seattle, Wash
Spokane, Wash
Springfield, Mass.
Eyracuse, N. Y
Tacoma, Wash
Toledo, Ohio.
Trenton, NJ
Washington, D.C.
Worcester, Mass
Yonkers, N. Y.

19.7, 901

770, 400
3143, 555

536,718
111, 144

124, 157
42, 833, 288

405,312 877, 992 261,082 177, 274 163, 530 272,031 3 993, 678

106, 289 112, 371 120, 912 117,968 123.021 115, 917 151, 970 340, 552 100, 016 309.03-1 113, 781 351,319 666, 853 257,671 115, ON9 170, 057 481, 595 409, 123 121. 123 130, 072 172, 967

401, 575 5,927, 625

810, 514
2,156, 657
2, 267, 001

535, 814
127, 519

438, 699
4 124,915
240, 086
204,382

139, 579 1.922.788 1 607, 902

273, 621 212, 378 181,014 317, 867 803, 853 245,891 126,241 181, 727 539, 038 € 315, 312

104, 573 144, 227 184,511 101, 731 266,338

127.390
3 437, 571

191, 927
107, 520

16.2 20.6 16.7 14.8 17.3 24.8 11.5 21.3 12. 20. + 15,3 12.6 17.1 15. 1 10.8 12.5 19.0 11.5

8. S 16.4 13,1 14.1 18. 8 13. 16.7 17.0 16.5 18.0 18.1 26.1 11.3 11,2 28.4 15.6

9.9 18.8 12.8

9.5 11,5 15.7

8,5 23.3 13, 0 15.9 15.0 10.5 10,5 19. 2 21.2 11.9 24. 3 15.6 14.1 13.8 11.4 13.6 16,1 15,3

9.3 10.5 11.2 15. 5

8. 2 14.0 21.7 18. 1 13.6 12. 1

[blocks in formation]

5.9 11.3 11.8 12.3 13.9 14.0 17.0 14.6 14.7 13. 1 10.9 20.5 il. O 10.4 19.5 13.3 13,8 19.7 14.1 11.4 12.9 16.6 10,8 21.8 13.3 10.9 13.4 18.7 12. 8 15.4 16.6 13.0 15.8 15.5 10. 2 15.7 10.4 16.4

13 208 19 73 93 15

4 16 5

55 90

64

[blocks in formation]

4

109 42 88 103 87 16 101 125

61 114 117 126

[blocks in formation]

55 16

28 708 217

78 113 51 86 212 53 33 57 158 56 21 31 55 16 72 53 152 50 25

[blocks in formation]

72 62

[blocks in formation]

43 91 75 91 51 69 56 87

* Enumerated population Jan. 1, 1920.

* Estimated population July 1, 1922.

« ForrigeFortsett »