Binny, in all of whom, as well as in the three children of the 10th regiment, I had an opportunity of observing the progress of the infection; and, from comparing the symptoms and appearances produced by it, with the minute and circumstantial descriptions given by Dr. Jenner, Mr. Aiken, and Dr. De Carro, and with the coloured plates, by which their descriptions are illustrated, I am perfectly satisfied that it was the true vaccine disease. Messrs. Russells, Hare, Shoolbred, and other medical gentlemen, who had an opportunity of seeing the children, are fully impressed with the same conviction.

"In confirmation of this im portant fact, I think it proper to mention that three children who were inoculated with the thread sent me by captain. Anderson from Kedgeree, as mentioned in his let-ter, received the infection, and shewed, in the progress of the discase, the same characteristic symp. toms and appearances on the arm as those that were inoculated from -Norton.

"The same satisfactory result was experienced in respect to two children inoculated by Mr. Shoolbred on the 20th, and two others on the 21st, from matter taken from Norton's arm on the 19th; all of whom, he assures me, exhibited, in the most unequivocal manner, the distinguishing symptoms of the genuine cow-pox.

"The settlement being how, as I conceive, in complete possession of the benefit derived to mankind from Dr. Jenner's celebrated discovery, I take the liberty of submitting to your excellency's consideration my opinion on the best mode of preserving the continu

ance of so great a blessing, and spreading it as rapidly as possible throughout the provinces.

"For attaining the first of these important objects, I would recommend that a surgeon of approved skill and assiduity should be appointed to the charge of preserving a constant supply of recent genuine matter, for the use of the metropolis and the subordinate stations; and that it should be a part of his duty not only to vaccinate the children of such of thre natives as might apply to him, but also to take every opportunity to instruct the Hindu and Mahommedan physicians in the proper mode of performing the operation and to give them precise and clear information respecting those symptoms and appearances by which the specific genuine cow-pox may be distinguished from other eruptions.

"To facilitate the general adoption of the practice of vaccination by the natives, I beg leave to suggest that a notification should be published in the Persian, Hinduee, and Bengalese languages, and also in the Sanscrit, giving—

"1. A succinct history of the discovery, in which the curious, and, to the Hindus, very interesting circumstance, that this wonderful preventive was originally procured from the body of the cow, should be emphatically remarked.

"2. An explanation of the important and essential advantages which vaccination possesses over the small-pox inoculation, and

"Lastly, an earnest exhortation to the natives of these provinces to lose no time in availing themselves of this inestimable benefit, scarcely inferior to any that ever was com municated

2

Fort St. George, Oct. 11, 1802. "Dear Sir,

"Not having heard of the Bombay cow-pox matter succeeding in Bengal, I take the opportunity of the ship Hunter sailing to inoculate two boys born of European parents at Botany Bay (where the small-pox has never appeared), never appeared), belonging to the ship, by whom captain Anderson, the commander, hopes of being able to continue the disease in succession, until his arrival at Calcutta.

"The matter with which these two boys have been inoculated was taken, last night, from the arm of a healthy child inoculated at Chingleput on the 1st instant, with threads sent on the 9th ultimo from Trincomalee, by Mr. Rogers.

The disease appears to all here to be of the genuine kind; and confident of your attention to promote the benefit of this invaluable discovery,

"I am, very truly, your's, (Signed) "J. ANDERSON." JOHN FLEMING, esq.

Calcutta.

(COPY.)

JOHN FLEMING, esq.

66 Sir,

have the pleasure of sending you the following memorandums re-. specting the persons I inoculated for the cow-pox during my passage from Madras.

"John Cresswell, a boy born at Port Jackson, of European parents, aged about 13 years, inoculated at Dr. Anderson's house, at Madras, on the 10th of October, from a native child, who had arrived that day from Chingleput.

"As the disease made its appearance rather late, and afterwards advanced very slowly, I did not take matter from him till the 22d ultimo, when I inoculated M. A. an European child, aged 18 months: from her I inoculated Harry, a Malay boy, aged about 7 years, on the 2d of November; and on the 12th, Charles Norton, a boy born at Port Jackson, of European parents, aged about 15 years, was inoculated from Harry. The disease having made its appearance in due time, as soon as the ship arrived at Diamond Harbour, I sent him to town, where he arrived on the 19th instant, and was disposed of as you directed.

"The cotton threads which I sent you from Kedgeree were strongly impregnated with vaccine matter taken from the European child and the Malay boy on the 2d and 12th instant, as particularly marked on each.

"I have the honour to be,
"Sir,

"Your most obedient

"Humble servant,

.

The governor general in council

1st. That the high approbation of his excellency in council be signified to Dr. James Anderson, physician general and first member of the hospital board, upon the establishment of Fort St. George, for the benevolent attention, assiduity, and skill manifested by him in promoting the introduction into these provinces of the benefit of the valuable and important discovery made by Dr. Jenner; and that this order be transmitted to the right honourable the governor in council of Fort St. George, for the purpose of being duly signified to Dr. Anderson.

2d. That the chief secretary do signify to captain Anderson, commander of the ship Hunter, the thanks of the governor general in council, for his assiduous attention in insuring the success of the important commission with which he was entrusted.

3d. That the chief secretary 'do signify the approbation of the governor general in council to John Fleming, esq. and to Messrs. Russell, Hare, and Shoolbred, and the other medical gentlemen employed on this important occasion, for their diligence and ability, in promoting at this presidency the successful introduction of Dr. Jenner's discovery.

4th. That Mr. William Russel be appointed to superintend the further promotion of the benefits of Dr. Jenner's discovery throughout the provinces subject to the immediate government of this presidency.

5th. That a notification be prepared and published in the Persian, Hinduee, Bengalese, and Sanscrit languages, a cording

3

MAY, 1802.

Mr. Francis Macnagh en, to be standing counsel to the honourable company. Mr. J. W. Sherer, to be head assistant in the office of the accountant general. Mr. George Ravenscroft, to be deputy paymaster and commissary of bizars, at the station of Berhampoor, in the room of Mr. C. T. Clarke, appointed colice

tor of Berboom. Mr. Christopher Qldfield, to be third judge of the provincial court of appeal and court of circuit for the division of Moorshadabad.

Mr. John Rawlins, to be third judge of the provincial court of appeal and court of circuit for the division of Patna, Mr. W. W Massie, to be judge and magistrate of the zillah of Nuddeah. Mr. W. Cowell, to be judge and magistrate of the zillah of Shahabad.

Mr. J Deane, to be judge and magistrate of the zillah of Juanpore.

Sir A. Seton, bart. to be judge and magistrate of the zillah of Berboom. Mr. D. Campbell, to be judge and magis-trate of the zillah of Rajeshahce. Mr. J. B. Laing, to be register to the provincial court of appeal and court of circuit for the division of Dacca. Mr. W. Brodie, to be register to the provincial court of appeal and court of circuit for the division of Morshidabad. Mr. E. Parker, to be register ote Dewannee Adawlut, and assistant to the magis trate of the zillah of Sarun.

Mr. R. Martin, to be register of the Dewan

nee Adawlut, and assistant to the magistrate of the zillah of Ramghur. Mr. G. Oswald, to be register of the Dewannee Adawlut, and assistant to the magistrate of the zillah of Burdwan. Mr. J. M. Rees, to be register of the

Dewannee Adawluf, and assistant to the magistrate of the zillah of Dacca Jelal

pore.

Mr. H. Somerville, to be register of the

Dewannee Adawlut, and assistant to the nagistrate of the zillah of Rungpore. Mr. C. Trower, to be register of the Dewannee Adawlut, and assistant to the magtrate of the zillah of Behar. Mr. C. F. Fergusson, to the register of the Dewaunee Adawiut, and asistant to the magistrate of the city of Benares. Mr. E. Watson, to be register of the Dewannee Adawlut, and assistant to the magistrate of the zilian of Shahabad. Mr. S. T. Goad, to be assistant to the register to the Court of Sudder Dewannee Adiwiat and Nizamut Adawlut. Mr. W. Spedding, to be register of the Dewannee Adawlut, and assistant to the magistrate of the zilah of Moorshadabad. Mr. R. O. Wynne, to be register of the

Dewannee Adawlut, and assistant to the magis rate of the zillah of Backergunge. Mr. R. Turner, to be assistant to the regis

ter of the Dewannee Adawlut, and second assistant to the magistrate of the zillah of Behar.

M. C. T. Clarke, to be collector of Beerboom.

Mr. J. Miller, to be collector of Nuddeah, Mr. C. R. Bunt, to be collector of Dacca Jelalpor

Mr. J. Paule, to be collector of Rajeshakee. Mr. G. C. Master, to be assistant to the collector of Benares.