the solutions employed have not been recorded. are given only for : 10 The complete data Lævo-rotatory camphene. Terecamphene, C10 H16, obtained by heating terebenthene-chlorhydrate with an alcoholic solution of potash or with stearate of soda. Riban (Bull. soc. chim. 24, 10) found for alcoholic solutions with q = 62 to 90 per cent. alcohol, at a temperature of 13° to 14° : [a]d - (53·80 — 0·03081 q). = Commercial ethereal oils, being invariably mixtures of substances often of opposite optical powers, exhibit so much diversity in respect of rotation values, that these are of no use as a test of their purity, and special data are accordingly worthless. § 118. Resins. Euphorbone, C15 H24 O (from euphorbia resin). Dextro rotatory. Chloroform. Ether. c = 4. t = 15. (d = 0·72). c = 4. t = 15. [a]D = 18.8. Hesse (L. A. 192, 195). [a]D = 11.7. Podocarpic acid, C17 H22 Og. Dextro-rotatory. Laurel-camphor, C10 H16 O. Dextro-rotatory. For specific rotation in various solvents (§ 36, p. 84). The following others have been obtained :- Arndtsen (A. C. P. [3] 54, 418) has determined the specific rotation in alcoholic solutions for different rays, and with different weight-percentages of alcohol (q). t = 22.9°. The formulæ hold Dextro Camphoric acid, from laurel-camphor, C10 H16 04: 10 In Alcohol. [a]D 4° 21.5. [α]D 46.0. Landolt. Solutions in water. 9. = t = 20. (NH4), . Cho Hạ Oạc = 4 17. 14 t = 20. [α]D 16.98 0.13 c. Landolt. Methyl-camphoric acid, CH3. C10 H15 04 Dextro-rotatory. Alcohol. p = 143.04. t = 19.3. [a]; = 514. Loir (A. C. P. [3] 38, 485). For the rotatory power of other camphors and their derivatives no sufficient data exist. 0.873 at 15°. a, for 1 decimetre = 15.6). Schiff (L. A. 166, 94). 0.846 12.5°). Alcohol reduces specific rotation; ether, benzene, and oil have no effect. Petit (D. C. G. 1877, 896). Nicotine, C10 H14 No. Lævo-rotatory. (See § 32, p. 72.) CINCHONA ALKALOIDS. Besides those already given, §§ 103, 104, the following data have been further recorded, mostly by Hesse.1 1 Numerous earlier observations on the rotatory powers of alkaloids were made by Bouchardat (Ann. chim phys. [3] 9, 213), Bouchardat and Boudet (Journ. de Pharm. et de Chim. [3] 23, 288), Buignet (Journ. de Pharm. et de Chim. [3] 40, 268), De Vrij and Alluard (Compt. rend. 59, 201). These data are for Biot's red ray; but they are not now of much use, as the nature of solvent employed is scarcely ever recorded with sufficient exactitude. [The alcoholic chloroform mixture, much used by Hesse as solvent, consists of one volume alcohol of 97 per cent. (by volume) with two volumes chloroform.] Quinine hydrate, C20 H24 N2 O2 + 3 H20. Lævo-rotatory. 2 c 1.5 to 6. [a]D [α]D = + 1.0654 c2 141.0. 140·5. (158.7 1.911 c). (145.2 - 0.657 c). (165.81 8.203 c 0.04644 c3). Hesse (L. A. 176, 206). Lævo-rotatory. Alcoholic chloroform. In absolute and aqueous alcohol. Oudemans, p. 203. Quinine hydrochloride, C20 H24 N2 O2. HCl + 2 H2O. Lævo-rota Water (p. 199). Hydrochloric acid (p. 200). Absolute alcohol (p. 204). With aqueous alcohol, the specific rotation attains a maximum when the alcohol is in the proportion of 60 per cent. by volume. For c = 2, and t = 15°, the following values are given : The anhydrous compound dissolved in chloroform shows with c = 0.9 to 9 and (81.81 23.756 c + 3.9556 c2 0.2198 c3). - Solutions in dilute hydrochloric acid, with 1 molecule of the hydrochloride (c = 2) in 100 cubic centimetre solution, we have as follows: Diquinine sulphate (neutral), 2 (C20 H24 N2 O2). H2 S O1 + 8 H2 0. Lævo-rotatory. Absolute alcohol (p. 200). Aqueous alcohol (p. 200). = (157.5 0.27 c). 4 Hesse (L. A. 176, 213). -2 Quinine sulphate (Mono-acid), C20 H24 N2 O2. H2SO4 + 7 H2O. Lævo-rotatory. Water (p. 200). Absolute alcohol (p. 204). 2 t Alcoholic chloroform. In alcoholic solutions with c = 2, the specific rotation decreases 0.65° for each 1° rise of temperature. Draper (Silliman's American Journal), [3] 11, 42). Quinine disulphate (di-acid), C20 H24 N2 O2. 2 H2 S O4 + 4 H2 O. Lævo-rotatory. Quinine oxalate, 2 (C20 H21 N2 O2). C2 H2 O4 + 6 H2O. Lævo (L. A. 182, 44). Cinchonidine hydrochloride, C20 H24 N2 O . H Cl + H2O. Lævo rotatory. 2 Water (p. 201). Hydrochloric acid (p. 201). Absolute alcohol (p. 205). 2 Dicinchonidine sulphate, 2 (C20 H24 N2 O). H2SO4 + 6 H2 O. Lævo-rotatory. Water. c = 1.06. t = 15°. [a]D - 106.8. = Salt with 3 mols. water: alcohol of 80 per cent. (by vol.) c = 2. t = 15°. [a]D 144 5. Hesse (L. A. 176, 221). = Cinchonidine sulphate, C20 H24 N2 0 . H2 SO4 + 5 H2O. Lævo 2 C = 2. t 15°. Cinchonidine nitrate (p. 205). Cinchonidine oxalate, 2 (C20.H24 N„O). C1⁄2 H1⁄2 O1 + 2 H2O. Lævo rotatory. 2 4 2 Alcoholic chloroform. = 1 to 3. t = 15°. [a] = - 98.7. Hesse (L. A. 176, 222). Quinidine (conchinine) hydrate, C20 H24 N2 O + 21⁄2 H1⁄2 0. Dextro-rotatory. Alcohol of 97 per cent. (by vol.) (p. 201). 2 Quinidine hydrochloride, C20 H24 N2 0, . H Cl + H2 O. Dextro 2 rotatory. Water, hydrochloric acid (p. 201). Absolute alcohol (p. 205). 2 Acid salt: C20 H24 N2 O2. 2 HCl + H2O. Water. c = 2. t = 15°. [a]D ==== 250.3. Hesse (L. A. 176, 225). Diquinidine sulphate, 2 C20 H24N2 O2 . H2 SO4 + 2 H2 O. Dextro rotatory. Water. Sulphuric acid. Hydrochloric acid (p. 202). 2 Hesse (L. A. 176, 226). |