INTRODUCTION.

Of the Organical Sciences

THOUGH the general notion of life is acknowledged by the most

profound philosophers to be dim and mysterious, even up to the present time; and must, in the early stages of human speculation, have been still more obscure and confused; it was sufficient, even then, to give interest and connexion to men's observations upon their own bodies and those of other animals. It was seen, that in living things, certain peculiar processes were constantly repeated, as those of breathing and of taking food, for example; and that a certain conformation of the parts of the animal was subservient to these processes; and thus were gradually formed the notions of Function and of Organization. And the sciences of which these notions formed the basis are clearly distinguishable from all those which we have hitherto considered. We conceive an organized body to be one in which the parts are there for the sake of the whole, in a manner different from any mechanical or chemical connexion; we conceive a function to be not merely a process of change, but of change connected with the general vital process. When mechanical or chemical processes occur in the living body, they are instrumental to, and directed by, the peculiar powers of life. The sciences which thus consider organization and vital functions may be termed organical sciences.

When men began to speculate concerning such subjects, the general mode of apprehending the process in the cases of some functions, appeared to be almost obvious; thus it was conceived that the growth of animals arose from their frame appropriating to itself a part of the substance of the food through the various passages of the body. Under the influence of such general conceptions, speculative men were naturally led to endeavor to obtain more clear and definite views of the course of each of such processes, and of the mode in which the separate parts contributed to it. Along with the observation of the living person, the more searching examination which could be carried on in the dead body, and the comparison of various kinds of animals, soon showed that this pursuit was rich in knowledge and in interest.

Moreover, besides the interest which the mere speculative faculty gave to this study, the Art of Healing added to it a great practical value: and the effects of diseases and of medicines supplied new materials and new motives for the reasonings of the philosopher.

In this manner anatomy or physiology may be considered as a science which began to be cultivated in the earliest periods of civilization. Like most other ancient sciences, its career has been one of perpetual though variable progress; and as in others, so in this, each step has implied those which had been previously made, and cannot be understood aright except we understand them. Moreover, the steps of this advance have been very many and diverse; the cultivators of anatomy have in all ages been numerous and laborious; the subject is one of vast extent and complexity; almost every generation had added something to the current knowledge of its details; and the general speculations of physiologists have been subtle, bold, and learned. It must, therefore, be difficult or impossible for a person who has not studied the science with professional diligence and professional advantages, to form just judgments of the value of the discoveries of various ages and persons, and to arrange them in their due relation to each other. To this we may add, that though all the discoveries which have been made with respect to particular functions or organizations are understood to be subordinate to one general science, the Philosophy of Life, yet the principles and doctrines of this science nowhere exist in a shape generally received and assented to among physiologists; and thus we have not, in this science, the advantage which in some others we have possessed;-of discerning the true direction of its first movements, by knowing the point to which they ultimately tend;-of running on beyond the earlier discoveries, and thus looking them in the face, and reading their true features. With these disadvantages, all that we can have to say respecting the history of Physiology must need great indulgence on the part of the reader.

Yet here, as in other cases, we may, by guiding our views by those of the greatest and most philosophical men who have made the subject their study, hope to avoid material errors. Nor can we well evade making the attempt. To obtain some simple and consistent view of the progress of physiological science, is in the highest degree important to the completion of our views of the progress of physical science. For the physiological or organical sciences form a class to which the classes already treated of, the mechanical, chemical, and classificatory sciences, are subordinate and auxiliary. Again, another

circumstance which makes physiology an important part of our survey of human knowledge is, that we have here a science which is concerned, indeed, about material combinations, but in which we are led almost beyond the borders of the material world, into the region of sensation and perception, thought and will. Such a contemplation may offer some suggestions which may prepare us for the transition from physical to metaphysical speculations.

In the survey which we must, for such purposes, take of the progress of physiology, it is by no means necessary that we should exhaust the subject, and attempt to give the history of every branch of the knowledge of the phenomena and laws of living creatures. It will be sufficient, if we follow a few of the lines of such researches, which may be considered as examples of the whole. We see that life is accompanied and sustained by many processes, which at first offer themselves to our notice as separate functions, however they may afterwards be found to be connected and identified; such are feeling, digestion, respiration, the action of the heart and pulse, generation, perception, voluntary motion. The analysis of any one of these functions may be pursued separately. And since in this, as in all genuine sciences, our knowledge becomes real and scientific, only in so far as it is verified in particular facts, and thus established in general propositions, such an original separation of the subjects of research is requisite to a true representation of the growth of real knowledge. The loose hypotheses and systems, concerning the connexion of different vital faculties and the general nature of living things, which have often been promulgated, must be excluded from this part of our plan. We do not deny all value and merit to such speculations; but they cannot be admitted in the earlier stages of the history of physiology, treated of as an inductive science. If the doctrine so propounded have a solid and permanent truth, they will again come before us when we have travelled through the range of more limited truths, and are prepared to ascend with security and certainty into the higher region of general physiological principles. If they cannot be arrived. at by such a road, they are then, however plausible and pleasing, not portion of that real and progressive science with which alone our history is concerned.

We proceed, therefore, to trace the establishment of some of the more limited but certain doctrines of physiology.

IN

CHAPTER I.

DISCOVERY OF THE ORGANS OF VOLUNTARY MOTION.

Sect. 1.-Knowledge of Galen and his Predecessors.

N the earliest conceptions which men entertained of their power of moving their own members, they probably had no thought of any mechanism or organization by which this was effected. The foot and the hand, no less than the head, were seen to be endowed with life; and this pervading life seemed sufficiently to explain the power of motion in each part of the frame, without its being held necessary to seek out a special seat of the will, or instruments by which its impulses were made effective. But the slightest inspection of dissected animals showed that their limbs were formed of a curious and complex collection of cordage, and communications of various kinds, running along and connecting the bones of the skeleton. These cords and communications we now distinguish as muscles, nerves, veins, arteries, &c.; and among these, we assign to the muscles the office of moving the parts to which they are attached, as cords move the parts of a machine. Though this action of the muscles on the bones may now appear very obvious, it was, probably, not at first discerned. It is observed that Homer, who describes the wounds which are inflicted in his battles with so much apparent anatomical precision, nowhere employs the word muscle. And even Hippocrates of Cos, the most celebrated physician of antiquity, is held to have had no distinct conception of such an organ.' He always employs the word flesh when he means muscle, and the first explanation of the latter word (uus) occurs in a spurious work ascribed to him. For nerves, sinews, ligaments,' he used indiscriminately the same terms; (róvos or vsupov ;) and of these nerves (vsupa) he asserts that they contract the limbs. Nor do we find much more distinctness on this subject even in Aristotle, a generation or two later. "The origin of the vɛupa," he says, "is from the heart; they connect

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1

Sprengel, Geschichte der Arzneikunde, i. 382.

2

Sprengel, Gesch. Arz. i 385.

Hist. Anim. iii. 5.

the bones, and surround the joints." It is clear that he means here the muscles, and therefore it is with injustice that he has been accused of the gross error of deriving the nerves from the heart. And he is held to have really had the merit of discovering the nerves of sensation, which he calls the "canals of the brain" (ópos roũ synepáλov) ; but the analysis of the mechanism of motion is left by him almost untouched. Perhaps his want of sound mechanical notions, and his constant straining after verbal generalities, and systematic classifications of the widest kind, supply the true account of his thus missing the solution of one of the simplest problems of Anatomy.

In this, however, as in other subjects, his immediate predecessors were far from remedying the deficiencies of his doctrines. Those who professed to study physiology and medicine were, for the most part, studious only to frame some general system of abstract principles, which might give an appearance of connexion and profundity to their tenets. In this manner the successors of Hippocrates became a medical school, of great note in its day, designated as the Dogmatic school; in opposition to which arose an Empiric sect, who professed to deduce their modes of cure, not from theoretical dogmas, but from experience. These rival parties prevailed principally in Asia Minor and Egypt, during the time of Alexander's successors,—a period rich in names, but poor in discoveries; and we find no clear evidence of any decided advance in anatomy, such as we are here attempting to

trace.

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The victories of Lucullus and Pompeius, in Greece and Asia, made the Romans acquainted with the Greek philosophy; and the consequence soon was, that shoals of philosophers, rhetoricians, poets, and physicians streamed from Greece, Asia Minor, and Egypt, to Rome and Italy, to traffic their knowledge and their arts for Roman wealth. Among these, was one person whose name makes a great figure in the history of medicine, Asclepiades of Prusa in Bithynia. This man appears to have been a quack, with the usual endowments of his class; -boldness, singularity, a contemptuous rejection of all previously esteemed opinions, a new classification of diseases, a new list of medicines, and the assertion of some wonderful cures. He would not, on such accounts, deserve a place in the history of science, but that he became the founder of a new school, the Methodic, which professed to hold itself separate both from the Dogmatics and the Empirics.

Sprengel, Gesch. Arz. i. 583. Sprengel, Gesch. Ar..... ii, 5