The Slow Inward Current and Cardiac Arrhythmias, Volum 7Douglas P. Zipes, J.C. Bailey, V. Elharrar BRILL, 30. nov. 1980 - 521 sider Since Paul Cranefield published his monograph, The Conduction of the Cardiac Impulse, in 1975, much has been learned about the role of the slow inward current in cardiac electrophysiology. Because of this expanse in know ledge, both basic and clinical, it appeared reasonable to review in a mono graph once again what was known. When Martinus Nijhoff first approached us to undertake the task of updating this information, we were initially reluctant for several reasons. First, we did not feel that the subject could be adequately and thoroughly reviewed, from the cell to the bedside, by a single person. Second, time constraints on all of us precluded even attempting such a task. However, we were encouraged by several of our friends (' egged on' one might even say, since they wished the job done but did not want to do it themselves!) who promised faithfully to contribute chapters on time if we accepted the task. So we did, and most of them did also. |
Innhold
Historical perspective | 3 |
The slow response and cardiac arrhythmias | 11 |
Voltage clamp studies of the slow inward current | 25 |
nonvoltageclamp studies | 97 |
The role of cyclic AMP in regulation of the slow inward cur | 111 |
The role of the slow inward current in impulse formation | 127 |
Slow conduction in the heart | 149 |
Slow inward current and contraction | 173 |
The slow response in human ventricle | 309 |
The role of electrotonus in slow potential development | 327 |
Voltage modulation of automaticity in cardiac Purkinje fibers | 357 |
Depolarizationinduced automaticity in atrial and ventricular | 372 |
Role of the slow current in the generation of arrhythmias | 399 |
Digitalisinduced delayed afterdepolarizations | 417 |
Triggered activity | 437 |
Effect of antiarrhythmic drugs on the slow inward current | 455 |
Effects of neurotransmitters on the slow inward current | 205 |
The slow inward current of the rabbit sinoatrial nodal cells | 265 |
The slow response in human atrium | 295 |
The role of the slow inward current in the genesis and main | 481 |
Andre utgaver - Vis alle
The Slow Inward Current and Cardiac Arrhythmias Douglas P. Zipes,J.C. Bailey,V. Elharrar Begrenset visning - 2012 |
The Slow Inward Current and Cardiac Arrhythmias, Volum 7 Douglas P. Zipes,J.C. Bailey,V. Elharrar Ingen forhåndsvisning tilgjengelig - 1980 |
The Slow Inward Current and Cardiac Arrhythmias Douglas P. Zipes,J.C. Bailey,V. Elharrar Ingen forhåndsvisning tilgjengelig - 2011 |
Vanlige uttrykk og setninger
acetylcholine Amer J Physiol amplitude Arch ges Physiol atrium AV node block calcium canine cardiac action potential Cardiac Arrhythmias cardiac muscle cardiac Purkinje fibers Cardiol catecholamines Circulat Res concentration contraction coronary Cranefield PF cycle length cyclic AMP decrease delayed afterdepolarizations diastolic depolarization effects of verapamil electrophysiologic electrotonic excitation fibres Figure guinea pig Hoffman BF hyperpolarizing impulse inactivation increase induced inotropic intracellular ionic ions ischemic isoproterenol lidocaine mammalian maximum diastolic potential mechanism membrane currents membrane potential msec myocardium nodal cells normal occur outward current overdrive pacemaker panel permeability Pflügers Arch ges Physiol Lond plateau potassium pulse Purkinje fibers rabbit rate of rise reentrant reentry resting potential Reuter H sinus node slow Ca++ current slow channel slow inward current slow response sodium solution Sperelakis spontaneous stimulation studies superfusate tachycardia tetrodotoxin threshold tion transmembrane potential Trautwein triggered activity upstroke ventricular muscle verapamil Vmax voltage clamp Zipes