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American Druggist Prize Competition.

RIEF, bright essays on subjects of interest to pharmacists are invited for the Prize Essay Department of the AMERICAN DRUGGIST. For every article printed, long or short, the AMERICAN DRUGGIST will fortnightly pay $5.00.

Our object in inaugurating the Prize Essay Column was, as we have repeatedly urged, to secure the co-operation of our readers in making each issue of the AMERICAN DRUGGIST a practical means of enriching the general fund of information regarding druggists' methods and pharmaceutical manipulation, and our success has been well demonstrated by the many valuable papers already printed.

For the convenience of new readers and others who have not heretofore taken an active interest in the Prize Essay Column, we may state that preference is given to articles descriptive of new apparatus or of pharmaceutical contrivances; notes on new methods of preparing galenical compounds; dispensing difficulties solved; hints on window dressing; the care of the soda fountain; the best method of store arrangement and pharmaceutical formulas, including toilet preparations, perfumes, soda syrups and medicinal preparations.

The

While we have a large number of MSS. in hand, more are welcomed. selections for prizes are made in the order of the receipt of essays, but preference is always given to articles of special merit, so that intending contestants should not hesitate to send in essays on the ground of anticipated delay in publication and award, promptness of publication and award being determined by the character of the essay as well as the order of receipt.

Those intending to compete are again reminded that comparatively brief and business-like essays will be regarded by the Prize Essay Editor with more favor than lengthy papers on abstruse matters or of a purely scientific character.

Essays for competition should be addressed,

PRIZE ESSAY EDITOR,

American Druggist, 66 West Broadway, New York.

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Vol. XXXIV. No. 5.

Whole No. 419.

and Pharmaceutical Record.
"America's Leading Drug Journal: Founded

ISSUED SEMI-MONTHLY BY

NEW YORK AND CHICAGO, MARCH 10, 1899.

AMERICAN DRUGGIST PUBLISHING CO
62-68 WEST BROADWAY, NEW YORK.
Telephone, 4470 Cortlandt.
A. R. ELLIOTT, President.

Editor.

CASWELL A. MAYO, Ph. G......
THOMAS J. KEENAN.. ..Associate Editor.
IRVING J. BENJAMIN.... Business Manager.

Chicago Office, 221 Randolph Street.

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Manager.

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TABLE OF CONTENTS.

EDITORIALS

PRIZE ESSAY:

SOME BENEFITS OF ORGANI

ZATION.

Issued Semi-Monthly.

clerk actually works while in attendance in the store, and drew lurid pictures of the "terrible effects" of overworking the drug Not

ONE of the best texts for a sermon sorts of crime at thcontent with laying all

tion which has come to our notice
of late was a case decided a short time
ago at Newburgh, in this State. The mer-
chants of Middletown formed an organi-
zation through which they were induced
to discontinue the use of trading stamps,
which had come to be universal and a
universal nuisance. The, trading-stamp
companies brought suit against the mer-
chants for conspiracy, and the case was
decided in Newburgh very promptly in
favor of the defendants, the judge tak-
ing occasion to denounce the entire trad-
ing-stamp scheme. It will be borne in
mind, by the way, that the use of these
stamps has been declared illegal in
Michigan and several other States, and
that local associations have frequently,
by concerted action, rid themselves of
this incubus, which, had the associations
been sufficiently active and far-sighted,
would never have been fastened on the
trade. During the past year four States,
Virginia, Maryland, Massachusetts and
Vermont, have prohibited their use.
132
prohibiting act also passed the New Jer-
sey Legislature, but was vetoed by the
Governor.

..127, 128

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Collargol; The Guaiacolsulphonic Acids; Mutase; Chelidonine Sulphate; Change in Ointment of Yellow Mercuric Oxide; A Safety Bunsen Burner; The Influence of Borax on Digestion; Opalisin; A New Method of Estimating Pepsin; Preparation of Acoin Solutions; To Distinguish Between Ozone, Nitrous Acid and Hydrogen Dioxide; The Precipitate in Fl. Ext. Hydrastis; New Form of Bunsen Burner; A New Method for the Quantitative Estimation of Formaldehyde; The Chemical Constituents of Pichi-Pichi... .133-134 Ethyl Nitrite Apparatus, Estimation of.... 134 Bismuth in Bismuth Iodide Syrup of Hydriodic Acid; Microchemical Study of the Location of Alkaloid in Drugs..... Variation in Strength of Official Acids; The Sale of Poisons in Germany.. 136 New Poison Regulations in Great Britain.. 137 QUERIES AND ANSWERS:

Separation in a Prescription; Peau d'Espagne; Estimation of Fluid Extract of Liquorice; Eugulmine; Deposit in Syr. Hypophos. Co.; Roach Powder; Powder Dentifrice; Camphorated Chalk; Headache Powder Formulas; Window Dressing; Copying Ink..

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The latest necessity for organization among the retail druggists of New York has arisen through the pernicious activity of an individual connected with the labor unions, who is exerting himself to have the control of pharmacy matters taken out of the jurisdiction of the Board of Pharmacy and placed in charge of the Board of Health, with the incidental purposes of bringing pharmacy under the influence of politics and drug clerks into the labor unions. To this end the individual in question has kept the public mind in a state of alarm through the publication in the sensational press of artfully-concocted stories which tell of the depravity of the retail druggists in compelling their assistants to attend in the store a larger number of hours than the day laborer or mechanic works. He proceeded on the theory that the drug

ing druggist, and having exhausted the sympathy "racket" with the gullible individuals who supported his agitation to the extent of contributing money for the maintenance of the chief agitator, he boldly charged the retail druggists with being substituters of inferior for genuine drugs, and attempted, at the same time, to trace every case of accidental or willful poisoning to the carelessness of the proprietor-where it was not claimed that error arose from sleepy and overworked clerks. The trade endured these attacks in silence for a long time, or until patience ceased to be a virtue, but in seeking a remedy the druggists found themselves confronted with the fact that they had no organization to appeal to for aid. The druggists of Brooklyn met the attacks which appeared in the newspapers of that borough through the officers of the Kings County Pharmaceutical Society, an organization which has been of immense benefit to the trade there. Very late in the day, and after a bill calculated to interfere seriously with the professional practice of pharmacy in this city had been introduced in the State Legislature, at the instance of the labor-union agitator, the College of Pharmacy of the City of New York took action looking to the disabusing of the public mind of the impression that the "League for Shorter Hours," of which the agitator was the business agent, had any support from the retail druggists of New York. But, as we have said before, the College of Pharmacy is not thoroughly representative of the business men in pharmacy, and the feeling grew strong for the organization of an association of retail druggists, who were or had been carrying on business in New York City.

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the interval between meetings, has had its time fully occupied with the consideration of a number of bills inimical to the drug interests which have been introduced in the State Legislature during the present session. The Association has joined with the Drug Trade Section of the New York Board of Trade and Transportation, and the Committee on Proprietary Goods of the National Wholesale Druggists' Association, in bringing opposition to bear against the passage of four bills which, if passed, would cause a great deal of annoyance and expense to both the wholesale and the retail trade, and would not in any way be conducive to public welfare.

The need for an organization of retail druggists for business purposes, such as is represented by the Manhattan Pharmaceutical Association, has been realized as much by the wholesalers and manufacturers as by the retailers themselves, one of the best evidences of which is to be found in the earnest interest which is be

ing taken in the new Association by the wholesale trade, which has welcomed it in the most cordial manner. The Drug Trade Section of the Board of Trade and Transportation recognize that they have found a good ally in the M. P. A. in the furtherance of measures for the protection of the trade, and closer and better relations with the wholesalers and manufacturers are certain to result from the union.

PHARMACY LEGISLATION.

M SSACHUSETTS.

To paraphrase the weather prophet of the old-fashioned almanac we might say "About this Time look out for Pharmacy Legislation." In Massachusetts there are a half a dozen bills in the State Legislature affecting pharmacy either directly or indirectly. The same is true in New York and Illinois, while to a lesser extent a similar state of affairs exists in the legislatures of many of the principal .States.

Massachusetts still leads the van in its satisfactory treatment of the druggists' liquor tax problem. Efforts made by some of the druggists of Massachusetts to take the annual granting of certificates of fitness for a liquor license out of the hands of the Board of Pharmacy were strenuously opposed by representatives of temperance organizations on the ground that the local authorities refuse to act where druggists were selling liquor contrary to law, in marked contrast with the Board of Pharmacy's method of investigating complaints and revoking licenses where an illegal business is being carried on. It is with much pride that we point to this attitude on the part of the temperance organizations, for they were at one time the most bitter opponents of the

present law, which places the responsibil-
ity and authority for the regulation of the
liquor traffic by druggists in the hands of
the Board of Pharmacy. Experience has
evidently demonstrated even to these
doubting Thomases that no better method
can be devised of treating this delicate
question than that adopted in Massachu-
setts, which leaves the protection of the
fair name of the pharmacist in the hands
of the pharmacist himself. To all who
have anything to do with liquor legisla-
tion we would commend the example
both of the Legislature and of the Board
of Pharmacy of the State of Massachu-

setts.

NEW YORK.

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Among the half-dozen A

or SO bills affecting
pharmacy which are pending in the New
York State Legislature is one creating a
single Board of Pharmacy for the entire
State to replace the three boards which
now divide the responsibilities, the offices
and the fees. While we have always ad-
vocated a single board for the entire
State, it unfortunately happens that the
measure which has been introduced to

bring about this end is weak in many
particulars. While the Mazet bill, pro-
viding for a new pharmacy law for the
city of New York, is lamentably defic-
ient in all that concerns the regulation of
the sale and dispensing of poisonous sub-
stances, it is complete and comprehensive
as regards the regulation of the practice
of pharmacy generally. The substitution
of inferior for genuine drugs is guarded
against and penalties are provided for
against anyone convicted of this offense.
This provision distinguishes the proposed
law for New York City above any other
yet introduced in this State, and is in
marked contrast to the weakness of the
Poison Section, which is antiquated to a
degree and incongruous with the up-to-
date character of the rest of the bill.

Much can be said for and against all
three of the bills which have been intro-
duced in the Legislature for the regula-
tion of pharmacists in the State of New
York, and opinion among those who have
studied the subject is very much divided
as to which bill should have the prefer-
ence. The New York State Pharmaceu-
tical Association has declared itself in
favor of and is pushing the "All-State
bill."

The New York State Board of
Pharmacy, together with a certain fol-
lowing, is advocating the passage of cer-
tain amendments to the State bill now in
force, while the New York City Board of
Pharmacy and the pharmaceutical organ-
izations of New York City would like to
see the pharmacy chapter of the Greater

New York Charter amended along the
lines of the Mazet bill, which would leave
the regulation of pharmacy in the city
of New York entirely in the hands of
New Yorkers represented by the College

DECISION has at last been rendered in the United States Supreme Court in the warmly-contested alcohol rebate case adversely to the claimants for rebate. The claims, which amounted to several million dollars, were based upon Section 61 of the Wilson Tariff law, which went into effect on August 28, 1894, and was repealed on June 3,. 1896. The attorneys for the claimant have filed a motion for the rehearing of the case, which motion will be heard "in

chambers," and in view of the character of the decision rendered by the Supreme Court, it is highly improbable that this application will be granted, the general opinion being that the case may be looked upon as having been definitely settled adversely to the claimants.

The question of the effect which the granting of tax-free alcohol for use in pharmacy would have had on the retail drug trade has been discussed in these columns and a mature consideration of the problem leads to the conclusion that almost the entire body of retail druggists would have been unfavorably affected by any regulations which it would be feasible for the Government to put into force in granting tax-free alcohol for use in medicine unless it was specified that the alcohol should not be a constituent of the finished product.

With such a wide difference of opinion among persons in a position to have expert knowledge of every phase of the subject, with a rapidly growing governmental expense account and with appropriations for more than a billion and a half by the Congress just closed, the drug trade need feel no uneasiness as to a possibility of any material change in the direction of free alcohol for the arts, for whatever of good or of evil there might be for the trade in free alcohol is not to be reckoned with in the near future.

Cannot Do Without It.

Enclosed find check of $1.50, subscription for the AMERICAN DRUGGIST for the year 1899. I cannot do without it. It is part of our family. E. P. MANVILLE.

Whitehall, N. Y.

Prize Essay.

Brief, bright essays on subjects of interest to pharmacists are invited for the Prize Essay Department of the "American Druggist." For every article printed, long or short, the "American Druggist" will fortnightly pay $5.00.

NOTE ON SYRUP OF

FERROUS IODIDE.

BY W. A. DAWSON,
Hempstead, L. I.

UCH has been written on the sub

iodide in dispensable condition. owing to its proneness to decompose by part of the iodine being released.

I have used the U. S. P. formula and have found no difficulty in keeping the syrup in good condition for any reasonable length of time. I usually make sufficient to last several months at a time, and have kept it a year without change. I always choose a sunny day for making this preparation and the whole operation is conducted in direct sunlight. Sometimes when time was of no moment I have omitted the heating at the end of the reaction; instead, setting the flask containing the iron, iodine and water where the sun would shine on it for a day or two. The syrup so made seemed to keep quite as well as where heat was used. When finished, the syrup was decanted into quart, white flint glass bottles, cork stoppered, and placed on a white sheli that ran across the sunniest window of the laboratory, so that it would get all the sunlight possible.

Dispensing is done from these containers and no precautions are taken about keeping the containers full or securely stoppered. The temperature has varied from 30 to 100 degrees Fahrenheit at different times of the year, so the corks are usually lightly inserted to accommodate these changes. Kept thus in full sunlight the syrup keeps perfectly its characteristic light green color.

Diffused light of any degree decomposes the syrup in a short time. Absolute darkness retards decomposition, but does not prevent it. Colored glass containers do not seem to retard decomposition; in fact, amber glass seems to hasten it. I have often wondered why some manufacturers send out this syrup in amber glass

CAUTION.

Keep this medicine in a sunny place. If the liquid has turned brown, it should not be taken, as it is then irritating to the stomach. Set the bottle in the sunlight until the liquid turns white. It is then fit for use again.

bottles. Also have I wondered why so many pharmacists will pay manufacturers 60c. a pound or more (12 fluid ounces) for a preparation that is so quickly and easily made as syrup of ferrous iodide.

This syrup should be dispensed in white glass bottles bearing a label worded like the one here shown.

RECENTLY INTRODUCED

T

REMEDIES.

With Notes on Their Properties and Uses. HE following list, which is based upon one published by Prof. H. Beckurts in the "Apotheker Zeitung," embraces the more important and probably some of the less important remedies introduced to the profession since last July. Several of the remedies referred to as new by Prof. Beckurts are only new to Germany, having been known and used for some time outside of that country. No effort has been made to collect data concerning all the proprietary preparations launched during the period under review, only those being mentioned here which have chanced to come to the notice of the editor and concerning the properties or composition of which something more or less definite has been published. No responsibility is assumed for the statements here made, which are based upon the published notes in various pharmaceutical journals or upon the statements of the manufacturers:

ACETYL-PHENETIDIN-SULPHONATES: Made by heating a sodium or other salt of phenetidinsulphonate with glacial active acid (Ap. Zeit., 1898, No. 95). Their uses are not stated. Made by Hoffman, La Roche & Co.

ACIDEOLITH: A disinfectant of unknown composition containing sulphur.

ACOIN: Dipara-anisyl-mono-phenetyl-guanidin-chloral-hydrate. Local anaesthetic to replace cocaine; corrosive when used in concentrated solution.

AFTANNIN: An infusion of herbs mixed with 5 per cent of glycerin and 1.5 per cent of formaldehyde. Recommended for foot and mouth disease in cattle and stock.

ALBUMEN SOLUBLE: See soluble albu

men.

ALANTOL CIGARETTES: Cigarettes, made from tobacco containing but little nicotine and impregnated with a tincture of elecampane root.

AMYLENE CHLORAL: Oily heavy colorless liquid, camphoraceous odor and sharp cooling taste. Insoluble in cold water. Miscible in all proportions with alcohol, ether, acetone, etc.

ANTIPYRINE TANNATE: Yellow, tasteless powder, insoluble in water; containing about 37 per cent of antipyrine and 63 per cent of tannin. On contact with acids, it is resolved into its component constituents. Made by dissolving 3.2 Gms. of antipyrine in 10 Cc. of water, and mixing solution with a solution of 1.88 Gms. of tannin in a like quantity of water.

BALATIN: Thin, creamy sap of a South American tree. Forms a transparent, soft, impermeable non-irritating covering for wounds,

etc. Is miscible with water; coagulated by chloroform and alcohol.

BISMUTH OXY-IODIOXYPYROGALLATE: A brown, light, non-poisonous powder, permanent in the air. Made by Hoffman, Lá Roche & Co.

BOROL: Sodium boro-sulphate. For rendering interior of barrels aseptic. German patent.

CAPARRAPI OIL: An oil obtained from Nectandra Caparrapi, natural order Laurinee, found in Colombo. Recommended as substitute for copaiba balsam.

CARBONATED AMYL NITRITE: Amyl nitrite charged with carbon dioxide. Used to prevent disturbance of heart action caused by amyl nitrite alone.

CARBONATES OF THE PHENOLS, ETC.: These compounds have neither odor nor taste. They have been recommended as substitutes for the various bodies from which they are derived on this account. They are made by von Heyden of Radebeul, These compounds are prepared by acting on alcohols or phenols with phosgene and heating the resulting ester with guaiacol, methol or similar pheno-like bodies.

CHEIRANTHIN: Glucoside from leaves and seeds of cheiranthus cheiri. Yellowish white powder or crystal soluble in water alcohol ether, chloroform and acetone; unsoluble in ether and benzine.

CHLORALBACIDE: Compound of chlorine and albumen. A resinous crumbly mass insoluble in water. The alkaline salts are soluble. Dose, 7 to 22 grs. before meals. Recommended in faulty digestion, associated with diminished secretion of hydrochloric acid. Iodalbacide has also been made.

CHLORO-MONO-PHENOL:

This is used as an application in herpes tonsurans in a 20-per cent alcoholic solution. Details are not given in regard to its characteristics.

sol.

CINNAMYL-META-CRESOL: See HetocreCOLLODIAL MERCURY: See Hygrol. CREOSOFORM: A disinfectant compose of creosote and formaldehye.

CREOSOTE-FORMALIN: A mixture of 150 parts of creosote, 600 parts of formalin and 375 parts of oil turpentine. A disinfectant.

CRESAMINE: Mixture of ethylene diamine and tricresol. Antiseptic.

CRYSTALLIN: Mixture of one part of pyroxylin, four parts of methyl alcohol and fifteen parts of amyl acetate. Elastic crystallin is a mixture of twenty parts of crystallin, five parts of castor oil, ten parts of Canada balsam. It is to be used in the same way as collodion.

carbonate; made by Hefti, of Basel. DAVOSIN: Chocolate tablets of guaiacol

DIACETPHENETID: Brilliant, colorless needles, melting at 53.5° to 54°C, and boiling at 182°C. Soluble in alcohol, slightly in ether, almost insoluble in water. Hygroscopic. Action similar to that of phenacetin.

DIMETHYL-ETHYL-CARBONOL-CHLORAL: An oily colorless liquid with an odor of camphor, a cooling pungent taste, insoluble in water and miscible with alcohol, ether, acetone, chloroform and fatty oils. It is made by the action of amylene hydrate (Dimethyl-ethyl-carbonol) on chloral.

DIONIN: The hydrochlorate of monoethyl morphine. A crystalline, white, odorless, bitter powder, soluble in water, insoluble in ether and chloroform; melting point 123 degrees C. Used as a hypnotic and analgesic in place of codeine in the treatment of phthisis, asthma, pneumonia, etc. Dose, one-fourth to onehalf grain.

ELASTIN:

A fluid antiseptic covering for wounds, which congeals, forming a covering on the skin, and cannot be removed by water and soap. Made by Stephan, of Berlin.

EUDERMOL: Nicotine salicylate. Colorless hexagonal tables, melting at 117.5°C. Soluble in water. Externally in skin diseases.

EUGALLOL: Mono-acetate of pyrogallic acid. Thick, syrup, transparent mass of brownish yellow color, readily soluble in water. Marketed in 33 per cent acetone solution. Same uses as lenigallol, which is generally to be preferred.

EULACTOL: Dietetic preparation, said to contain all the necessary constitutents for sustenance.

EXTRACT OF FILIX SPINULOSA: Ethereal extract of the rhizome of aspidium spinulosum which has been recommended as a substitute for aspidium Filix-mas, as a taenicide.

FLUID ACETRACTS: Fluid extracts prepared by the use of acetic acid as a menstruum. FORMALDEHYDE STARCH AND GUM: Prepared by the action of formaldehyde upon starch, or gum, under pressure at a temperature of 100 to 150 degrees C., the product being subsequently purified. The compound is recommended as a means of applying formaldehyde.

Used both internally and in the form of an injection.

FORMALDEHYDE - TANNALBUMINATE COMPOUNDS: Prepared by the action of formaldehyde upon a previously prepared combination of tannin with albumen. The compound is insoluble in the stomach, but is decomposed in the intestinal tract, acting as an astringent and antiseptic. Made by Farbenfabriken-Elberfeld.

FORMALDEHYDE COMPOUNDS with phenols, naphthols, etc. These compounds are known as naphtho-formin, etc., and are prepared by mixing a solution of the phenol desired into a solution of formaldehyde in ammonia

water.

FORMOFERIN: A mixture of 0.13 parts of formaldehyde, 0.1 part of thymol, 34.5 parts of zinc oxide and 65.2 parts of powdered starch. Recommended as a foot powder.

GALLOFORMIN: Hard opaque needles, difficultly soluble in water, ether and glycerin, and insoluble in alcohol, benzol and fixed oils. Made by action of gallic acid of hexamethylene teramine. Decomposed, with liberation of formaldehyde, by either acids or alkalies.

GEMENOL: The oil of Melaluca Viridiflora, a plant of the order Myrtaceae, which is indig enous to New Caledonia. Recommended tuberculosis in capsules containing four grains each.

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ICHTHALBIN: A compound of albumen and ichthyol, prepared by adding ammonium sulphoicthyolate to a solution of albumen and subsequently adding diluted sulphuric acid. The dried product is freed from ethereal oil by heating or by treatment with alcohol, benzol or other solvent.

ICHTHYOL COMPOUNDS, tasteless: Prepared by treating metallic and earthy salts of ichthyol with alcohol, methyl alcohol or ether, or by heating the salts to 130 to 140 degrees C. Made by Cordes, Hermanni & Co.

IODOL MENTHOL: A mixture of 1 part of menthol with 99 of iodol.

KELENE METHYL: A mixture of chlorides of ethyl and methyl.

LENIGALLOL: Triacetate of pyrogallic acid. White powder, insoluble in water. Non-toxic, non-irritating application. Used in 0.5 to 5 per cent ointment. Eczema, etc. Preferable to eugallol.

LENIROBIN: Tetra acetate of chrysarobin. Less irritating than chrysarobin itself.

MARTOL: An extract of cocoa shells containing iron. Tonic in anaemia.

MERCURY COLLOIDAL: See Hygrol. META-CRESOL-ANYTOL: A solution containing 40 per cent of meta-cresol and 50 per cent of anytin (a 33 1-3 per cent aqueous solution of the alcoholic extract of ichthyol), recommended for external application in the treatment of erysipelas.

MILK-BRANDY: A German preparation made from coagulated milk and brandy.

NAPHTHO-FORMIN: Prepared like Resorcin-formin. A crystalline powder recommended as an intestinal antiseptic. See Formaldehyde compounds.

NEW ORTHOFORM: Meta-amido-para-oxybenzoic acid methyl ester. A fine white powder, which is less prone to agglutinate than orthoform itself. Recommended for use externally for wounds, burns, etc. Made by the Hochst Color Works.

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PHENOSALYL: Made by melting together 1 part of salicylic acid, 2 of lactic acid, 8 of carbolic acid and 0.1 part of menthol.

PHENOSOL: Para-phenetidin salicylate. Made by heating salicyl-acetic acid with paraphenetidin to 60 degrees C. Needles melting at 182 degrees C., difficultly soluble in water, alcohol and ether and easily decomposed into its component constituents by warming with alkali. Recommended as an antipyretic in the treatment of Ischia. Made by J. D. Riedel. PHTHISIN: Tablets made from extract of the bronchial gland. In lung affections.

an

POLYFORMIN SOLUBLE: Combination of two molecules of resorcin with one of hexamethylene tetramine. Handsome white crystals, antiseptic.

PRASOID: A solution of globularin and globularetin. Recommended for the treatment of gout and rheumatism.

PYROGALLOL COLLODION: A mixture of 1 part of pyrogallic acid, 2 of Canada fir and 17 of collodion. Recommended as a medium for applying pyrogallic acid to the skin which will not turn black.

PYROGALLOL-FORMIN: Prepared in the same way as resorcin-formin. (See below.) A voluminous, pale yellow powder which turns black, by oxidization, on exposure to the atmosphere.

PYROSAL: Acid salicylate of antipyrin. Crystals with a melting point of 149 to 150 degrees C., difficultly soluble in water, alcohol and ether and decomposed by either acids or bases into its component constituents. Made by J. D. Riedel. QUININ E UREO-HYDROCHLORATE: For malarial and intermittent fevers. Dose, about 9 grains.

to

RESORCIN FORMIN: This is prepared by pouring a soution of resorcin into a solution of formaldehyde into ammonia water. It forms a fine yellowish brown powder which is decomposed upon boiling with alkalies and then yields formaldehyde. This belongs to the class of "phenol-formaldehyde" compounds referred elsewhere in these columns as an antiseptic. SALICYL-GALLIC ACID: Made by heating a mixture of gallic and salicyic acids or of their salts with phosphorous oxychlorides or anhydride or some other dehydrating agents. Insoluble in water, ether and chloroform. Its uses have not been stated. Made by Farbenfabriken of Elberfeld.

SALIGALLOL: Disalicylate of pyrogallic acid. Solid, resinous body soluble in 2 parts of acetone and 15 parts of chloroform. Externally in skin diseases.

SANGUINOFORM: Claimed to contain neucleated blood corpuscles rich in hemoglobin and still able to develop. Dry powder. Tonic in anaemic conditions. Dose, half a teaspoonful.

SERO-ARSENIC: Normal serum containing sodium arsenite. Recommended as a clyster in the treatment of tuberculosis.

SERUM, Medicated: Defibrinated blood from domestic animals in which any desired medicament may be dissolved.

SODIUM ACET-PHENETIDIN SULPHONATE: A hygroscopic crystalline, reddish white mass, difficultly soluble in alcohol, insoluble in ether and readily soluble in water. May be used as a substitute for phenacetine.

SOLUBLE VEGETABLE ALBUMEN: The pressed cake of cotton seed, from which the oil has been extracted is powdered, suspended in water and treated with soda solution in order to dissolve the albuminous constituents. The solution thus obtained is filtered off, brought to dryness in a vacuum, the result being a sodium salt of the albumenoids in the form of a brown powder. This is dissolved, precipitated by the addition of an acid, the precipitate again dissolved in soda solution and finally evaporated to dryness. Prepared under patents of Meister, Lucius & Bruning.

TANNIN ALBUMINATES, Insoluble: Made by the action of formaldehyde upon albuminous compounds of tannin. Insoluble in the stomach, but dissolved in the intestines.

TANNIN-BISMUTH DERIVATIVES: Several tannin derivatives have been prepared to use either in the form of powder or in ointments for the treatment of wounds in the following manner: Either one or two molecules (for mono or dia-bismuth salt) of a bismuth salt, as for instance the nitrate is mixed with one or two molecules of an iodide and one molecule of tannic or any similar acid or with a condensation product of formaldehyde with tannin.

THYMOBROMAL: A mixture of extract of chestnut leaves, cold aqueous solution of thyme and bromal hydrate.

TRIBENZOYL-GALLIC ACID: Made by adding benzoyl chloride to a solution of gallic acid containing a caustic alkali. White, odorless, tasteless crystals, insoluble in water, which are not decomposed in the stomach but split up on entering in the intestines and are then absorbed. Made by Landshoff & Meyer.

TRIPHENETOL-GUANIDIN HYDROCHLORATE: Used as an anesthetic in ophtholmology. Made by von Heyden.

UNGUENTUM HYGROLI: Mercurial ointment made with hygrol (see above) instead of mercury.

UROPHERIN SALICYLATE: Salicylate of lithium theobrominate. Diuretic.

UROTROPIN SALTS: Various salts of hexamethylene-amine have been prepared and proposed for use in pharmacy. (Arch. de. Pharm., 1898.)

VANADIN: Solution of a vanadium salt with sodium chloride. Disinfectant.

VALERYDIN: Para-amido-phenetol valerianate. Snow white, shining needles melting at 129°C. Soluble in alcohol chloroform and acetone; less soluble in ether and almost insoluble in water. Sedative. Dose, 7 to 15 grs. several times daily.

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This may be perfumed with vanilla to disguise the odor of the oleate. The ammonia is added drop by drop until, after vigorous shaking, the odor can be barely detected. It is then allowed to stand for seven days and filtered through kaolin. Its cleansing properties are far above those of ordinary soap, and the alkalinity is scarcely noticeable.

A base containing wool-fat and lanolin soap, which can be used as an ointment or as a vehicle for the application of certain drugs, is made as follows:

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